Company Information
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell and natural killer (NK) cell-based immunotherapy.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel) in 2017. Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking Sr. Scientist, Vector Biology as part of the Research and Development team based in Philadelphia, PA.
Key Responsibilities
- Hands-on work in developing, performing and optimizing lentiviral vector (LVV) production.
- Design and test various LVV payloads for developing chimeric antigen receptor (CAR) T cell therapy.
- Upstream and/or downstream process development using suspension cell culture with scale up in bioreactor
- Works independently in planning, performing, analyzing, reporting and presenting experimental data and future technology transfer
- Supports LVV production for internal research teams
- Prepare all technical reports needed in support of an exploratory project moving to process development.
- Interacts cross-functionally within the process development and analytical organizations, as well as with other departments (regulatory, quality, manufacturing, clinical, supply chain).
Requirements
- BS degree with 4+ years; MS degree with 5+ years; PhD with minimum 3+ years in virology, molecular biology, cell & gene therapy or related field.
- Experience in lentiviral vector production and characterization
- Comfortable in a fast-paced biotech environment and able to adjust workload based upon priorities
#Li-JK1
#Li-Onsite
Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
Legend Biotech maintains a drug-free workplace.
